Center on Population Health and Aging
Biosketch - Gerald McClearn
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POSITION TITLE: Evan Pugh Professor of Health and Human Development and Biobehavioral Health
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SELECTED PUBLICATIONS: McClearn, G.E. , G.P. Vogler and R. Plomin (1996). "Genetics and Behavioral Medicine." Behavioral Medicine 22(3):93-102. |Abstract| |Journal Home Page| McClearn, G.E. and G.P. Vogler (1997). "Genetics and Behavioral Medicine: Error of the Error Term." Behavioral Medicine 22(4):150-151. |Journal Home Page| Vogler, G.P. , G.E. McClearn , H. Snieder , D.I. Boomsma , R. Palmer , P. de Knijff and P.E. Slagboom (1997). "Genetics and Behavioral Medicine: Risk Factors for Cardiovascular Disease." Behavioral Medicine 22(4):141-149. |Abstract| |Journal Home Page| Bonneau, R.H. , P. Mormede , G.P. Vogler , G.E. McClearn and B.C. Jones (1998). "A Genetic Basis for Neuroendocrine-Immune Interactions." Brain, Behavior, & Immunity 12(2):83-89. |Abstract| |Journal Home Page| McClearn, G.E. , L.M. Tarantino , S.M. Hofer , B.C. Jones and R. Plomin (1998). "Developmental Loss of Effect of a Chromosome 15 QTL on Alcohol Acceptance." Mammalian Genome 9(12):991-994. |Abstract| |Journal Home Page| Fernandez, J.R. , G.P. Vogler , L.M. Tarantino , S. Vignetti , R. Plomin and G.E. McClearn (1999). "Sex-Exclusive Quantitative Trait Loci Influences in Alcohol-Related Phenotypes." American Journal of Medical Genetics 88(6):647-652. |Abstract| |Journal Home Page| Johansson, B. , K.E. Whitfield , N.L. Pedersen , S.M. Hofer , F.M. Ahern and G.E. McClearn (1999). "Origins of Individual Differences in Episodic Memory in the Oldest-Old: A Population-Based Study of Identical and Same-Sex Fraternal Twins Aged 80 and Older." Journals of Gerontology--Series B: Psychological Sciences & Social Sciences 54B(3):173-179. |Abstract| |Journal Home Page| McClearn, G.E. and S.M. Hofer (1999). "Genes as Gerontological Variables: Genetically Heterogeneous Stocks and Complex Systems." Neurobiology of Aging 20(2):147-156. |Abstract| |Journal Home Page| McClearn, G.E. and S.M. Hofer (1999). "Genes as Gerontological Variables: Uniform Genotypes." Neurobiology of Aging 20(2):95-104. |Abstract| |Journal Home Page| Fernandez, J.R. , L.M. Tarantino , S.M. Hofer , G.P. Vogler and G.E. McClearn (2000). "Epistatic Quantitative Trait Loci for Alcohol Preference in Mice." Behavioral Genetics 30(6):431-437. |Abstract| |Journal Home Page| McClearn, G.E. and G.P. Vogler (2001). "The Genetics of Behavioral Aging." In Birren, J.E. and K.W. Schaie (Eds.) , Handbook of the Psychology of Aging, Fifth Edition. San Diego: Academic Press. McClearn, G.E. , G.P. Vogler and S.M. Hofer (2001). "Environment-Gene and Gene-Gene Interactions." In Masoro, E.J. and S.N. Austad (Eds.) , Handbook of the Biology of Aging, 5th ed.. Von Nostrand Reinhold. (pp. 423-444) Quirk, J.T. , S. Berg , V.M. Chinchilli , B. Johansson , G.E. McClearn and G.P. Vogler (2001). "Modelling Blood Pressure as a Continuous Outcome Variable in a Co-Twin Control Study." Journal of Epidemiology and Community Health 55(10):746-747. PMCID: PMC1731777?? |Full Text| |Journal Home Page| Hassing, L.B. , B. Johansson , S. Berg , S.E. Nilsson , N.L. Pedersen , S.M. Hofer and G.E. McClearn (2002). "Terminal Decline and Markers of Cerebro- and Cardiovascular Disease: Findings from a Longitudinal Study of the Oldest-Old." Journals of Gerontology B: Psychological Sciences/ Social Sciences 57(3):P268-P276. |Abstract| |Journal Home Page| Brandon, D.T. , K.E. Whitfield , J.J. Sollers , S.A. Wiggins , S.G. West , G.P. Vogler , G.E. McClearn and J.F. Thayer (2003). "Genetic and Environmental Influences on Blood Pressure and Pulse Pressure among Adult African Americans." Ethnicity and Disease 13(2):193-199. |Abstract| |Journal Home Page| Brandon, D.T. , K.E. Whitfield , J.J. Sollers , S.A. Wiggins , S.G. West , G.P. Vogler , G.E. McClearn and J.F. Thayer (2003). "The Nature and Nurture of Blood Pressure in African Americans." Ethnicity and Disease 13(2):297-298. |Journal Home Page| Kerin, T.K. , G.P. Vogler , D.A. Blizard , J.T. Stout , G.E. McClearn and D.J. Vandenbergh (2003). "Anogenital Distance Measures at Weaning is Correlated with Measures of Blood Chemistry and Behaviors in 450-Day-Old Female Mice." Physiology and Behavior 78(4-5):697-702. |Abstract| |Journal Home Page| Lionikas, A. , D.A. Blizard , D.J. Vandenbergh , M.G. Glover , J.T. Stout , G.P. Vogler , G.E. McClearn and L. Larsson (2003). "Genetic Architecture of Fast- and Slow-Twitch Skeletal Muscle Weight in 200-Day-Old Mice of the C57BL/6J and DBA/2J Lineage." Physiological Genomics 16(1):141-152. |Full Text| |Abstract| |Journal Home Page| Vandenbergh, D.J. , K. Heron , R. Peterson , K.B. Shpargel , A. Woodroffe , D.A. Blizard , G.E. McClearn and G.P. Vogler (2003). "Simple Tests to Detect Errors in High-Throughput Genotype Data in the Molecular Laboratory." Journal of Biomolecular Techniques 14(1):9-16. PMCID: PMC2279894?? |Abstract| |Journal Home Page| Whitfield, K.E. , D.T. Brandon , S.A. Wiggins , G.P. Vogler and G.E. McClearn (2003). "Does Intact Pair Status Matter in the Study of African American Twins?: The Carolina African American Twin Study of Aging." Experimental Aging Research 29(4):407-423. |Abstract| |Journal Home Page| Blizard, D.A. , D.J. Vandenbergh , A.L. Jefferson , C.D. Chatlos , G.P. Vogler and G.E. McClearn (2004). "Effects of Periadolescent Ethanol Exposure on Alcohol Preference in Two BALB Substrains." Alcohol 34(2-3):177-185. |Abstract| |Journal Home Page| Butler, R.N. , R. Sprott , H. Warner , J. Bland , R. Feuers , M. Forster , H. Fillit , S.M. Harman , M. Hewitt , M. Hyman , K. Johnson , E. Kligman , G.E. McClearn , J. Nelson , A. Richardson , W. Sonntag , R. Weindruch and N. Wolf (2004). "Biomarkers of Aging: From Primitive Organisms to Humans." Journals of Gerontology: Series A: Biological Sciences and Medical Sciences 59A(6):560-567. |Abstract| |Journal Home Page| Hassing, L.B. , M.D. Grant , S.M. Hofer , N.L. Pedersen , S.E. Nilsson , S. Berg , G.E. McClearn and B. Johansson (2004). "Type 2 Diabetes Mellitus Contributes to Cognitive Decline in Old Age: A Longitudinal Population-Based Study." Journal of the International Neuropsychological Society 10(4):599-607. |Abstract| |Journal Home Page| Hassing, L.B. , S.M. Hofer , S.E. Nilsson , S. Berg , N.L. Pedersen , G.E. McClearn and B. Johansson (2004). "Comorbid Type 2 Diabetes Mellitus and Hypertension Exacerbates Cognitive Decline: Evidence from a Longitudinal Study." Age and Ageing 33(4):355-361. |Abstract| |Journal Home Page| Jansson, M. , M. Gatz , S. Berg , B. Johansson , B. Malmberg , G.E. McClearn , M. Schalling and N.L. Pedersen (2004). "Gender Differences in Heritability of Depressive Symptoms in the Elderly." Psychological Medicine 34(3):471-479. |Abstract| |Journal Home Page| Johansson, B. , S.M. Hofer , J.C. Allaire , M.M. Maldonado-Molina , A.M. Piccinin , S. Berg , N.L. Pedersen and G.E. McClearn (2004). "Change in Cognitive Capabilities in the Oldest-Old: The Effects of Proximity to Death in Genetically Related Individuals over a Six-Year Period." Psychology and Aging 19(1):145-156. |Abstract| |Journal Home Page| McClearn, G.E. (2004). "Nature and Nurture: Interaction and Coaction." American Journal of Medical Genetics Part B-Neuropsychiatric Genetics 124B(1):124-130. |Abstract| |Journal Home Page| Nilsson, S.E. , S. Takkinen , B. Johansson , G. Dotevall , A. Melander , S. Berg and G.E. McClearn (2004). "Laxative Treatment Elevates Plasma Homocysteine: A Study on a Population-Based Swedish Sample of Old People." European Journal of Clinical Pharmacology 60(1):45-49. |Abstract| |Journal Home Page| Foreman, J.E. , D.A. Blizard , G.S. Gerhard , H.A. Mack , D.H. Lang , K.L. Van Nimwegen , G.P. Vogler , J.T. Stout , Z.K. Shihabi , J.W. Griffith , J.M. Lakoski , G.E. McClearn and D.J. Vandenbergh (2005). "Serum Alkaline Phosphatase Activity is Regulated by a Chromosomal Region Containing the Alkaline Phosphatase 2 Gene (Akp2) in C57BL/6J and DBA/2J Mice." Physiological Genomics 23(3):295-303. |Abstract| |Journal Home Page| Lang, D.H. , N.A. Sharkey , A. Lionikas , H.A. Mack , L. Larsson , G.P. Vogler , D.J. Vandenbergh , D.A. Blizard , J.T. Stout , J.P. Stitt and G.E. McClearn (2005). "Adjusting Data to Body Size: A Comparison of Methods as Applied to Quantitative Trait Loci Analysis of Musculoskeletal Phenotypes." Journal of Bone and Mineral Research 20(5):748-757. PMCID: PMC1201530?? |Abstract| |Journal Home Page| Lang, D.H. , N.A. Sharkey , H.A. Mack , G.P. Vogler , D.J. Vandenbergh , D.A. Blizard , J.T. Stout and G.E. McClearn (2005). "Quantitative Trait Loci Analysis of Structural and Material Skeletal Phenotypes in C57BL/6J and DBA/2 Second-Generation and Recombinant Inbred Mice." Journal of Bone and Mineral Research 20(1):88-99. PMCID: PMC1201529?? |Abstract| |Journal Home Page| Lionikas, A. , D.A. Blizard , G.S. Gerhard , D.J. Vandenbergh , J.T. Stout , G.P. Vogler , G.E. McClearn and L. Larsson (2005). "Genetic Determinants of Weight of Fast- and Slow-Twitch Skeletal Muscle in 500-day Old Mice of the C57BL/6J and DBA/2J Lineage." Physiological Genomics 21(2):184-192. |Abstract| |Journal Home Page| Whitfield, K.E. and G.E. McClearn (2005). "Genes, Environment, and Race: Quantitative Genetic Approaches." The American Psychologist 60(1):104-114. |Abstract| |Journal Home Page| Berg, A.I. , L.B. Hassing , G.E. McClearn and B. Johansson (2006). "What Matters for Life Satisfaction in the Oldest-Old?." Aging & Mental Health 10(3):257-264. |Abstract| |Journal Home Page| Blizard, D.A. , V.K. Weinheimer , L.C. Klein , S.A. Petrill , R. Cohen and G.E. McClearn (2006). "'Return to Home Cage' as a Reward for Maze Learning in Young and Old Genetically Heterogeneous Mice." Comparative Medicine 56(3):196-201. |Abstract| |Journal Home Page| Bower, A.L. , D.H. Lang , G.P. Vogler , D.J. Vandenbergh , D.A. Blizard , J.T. Stout , G.E. McClearn and N.A. Sharkey (2006). "QTL Analysis of Trabecular Bone in BXD F-2 and RI Mice." Journal of Bone and Mineral Research 21(8):1267-1275. |Abstract| |Journal Home Page| Lionikas, A. , M.G. Glover , F. Yu , L. Larsson , G.P. Vogler , G.E. McClearn and D.A. Blizard (2006). "Anomaly of Anatomical Origin of Soleus Muscle: A Mouse Model." Anatomical Science International 81(1):47-49. |Abstract| |Journal Home Page| McClearn, G.E. (2006). "Contextual Genetics." Trends in Genetics 22(6):314-319. |Abstract| |Journal Home Page| Proctor, D.N. , E.B. Fauth , L. Hoffman , S.M. Hofer , G.E. McClearn , S. Berg and B. Johansson (2006). "Longitudinal Changes in Physical Functional Performance among the Oldest Old: Insight from a Study of Swedish Twins." Aging Clinical and Experimental Research 18(6):517-530. |Abstract| Read, S. , N.L. Pedersen , M. Gatz , S. Berg , E. Vuoksimaa , B. Malmberg , B. Johansson and G.E. McClearn (2006). "Sex Differences after All Those Years? Heritability of Cognitive Abilities in Old Age." Journals of Gerontology Series B-Psychological Sciences and Social Sciences 61(3):P137-P143. |Abstract| Bakaysa, S.L. , L.A. Mucci , P.E. Slagboom , D.I. Boomsma , G.E. McClearn , B. Johansson and N.L. Pedersen (2007). "Telomere Length Predicts Survival Independent of Genetic Influences." Aging Cell 6(6):769-774. |Abstract| |Journal Home Page| McClearn, G.E. (2007). "Markers of Aging." In Birren, J.E. (Ed.) , Encyclopedia of Gerontology: Age, Aging, and the Aged. Elsevier. Blizard, D.A. , D.J. Vandenbergh , A. Lionikas and G.E. McClearn (2008). "Learning in the 2-Bottle Alcohol Preference Test." Alcoholism, Clinical and Experimental Research. |Abstract| |Journal Home Page| Vogler, G.P. and G.E. McClearn (2008). "Genetic Markers in Social Science Research: Opportunities and Pitfalls." In Weinstein, M. , J.W. Vaupel and K.W. Wachter (Eds.) , Biosocial Surveys. Washington, DC: National Academies Press. (pp. 194-207) |Full Text| Blizard, D.A. , A. Lionikas , D.J. Vandenbergh , T. Vasilopoulos , G.S. Gerhard , J.W. Griffith , L.C. Klein , J.T. Stout , H.A. Mack , J.M. Lakoski , L. Larsson , J.M. Spicer , G.P. Vogler and G.E. McClearn (2009). "Blood Pressure and Heart Rate QTL in Mice of the B6/D2 Lineage: Sex Differences and Environmental Influences." Physiological Genomics 36(3):158-166. PMCID: PMC2646459?? |Abstract| |Journal Home Page| Foreman, J.E. , A. Lionikas , D.H. Lang , J.P. Gyekis , M. Krishnan , N.A. Sharkey , G.S. Gerhard , M.D. Grant , G.P. Vogler , H.A. Mack , J.T. Stout , J.W. Griffith , J.M. Lakoski , S.M. Hofer , G.E. McClearn , D.J. Vandenbergh and D.A. Blizard (Forthcoming). "Genetic Architecture for Hole-Board Behaviors across Substantial Time Intervals in Young, Middle-Aged and Old Mice." Genes, Brain and Behavior. |Abstract| |Journal Home Page| |
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