Population Research Institute Social Science Research Institute Penn State
:. PRI :. Center on Population Health and Aging

Center on Population Health and Aging

Biosketch - George P Vogler


George P Vogler

Department Affiliation:  Biobehavioral Health
Education: PhD, Psychology, University of Colorado-Boulder, 1985
Directory Information

POSITION TITLE:  Professor of Biobehavioral Health and Director, Center for Developmental and Health Genetics

RESEARCH INTERESTS:  Genetic epidemiology of complex traits; quantitative trait loci mapping; cardiovascular disease; methodological issues in genetic models and structural equation models; behavioral moderation of expression of biological traits.

GRANTS: 

Center on Population Health and Aging (2004-2008)

Training in Genetics of Complex Behaviors in Aging (2005-2010)


PROFESSIONAL EMPLOYMENT AND EXPERIENCE: 

1978-1980 Research Assistant, Unit for Experimental Psychiatry, Institute of Pennsylvania Hospital and University of Pennsylvania, Philadelphia, PA

1980-1981 Teaching Assistant, Department of Psychology, University of Colorado, Boulder

1982-1985 Research Assistant, Institute for Behavioral Genetics, University of Colorado, Boulder

1985-1987 Instructor of Biostatistics, Washington University School of Medicine, St. Louis

1987-1995 Assistant Professor of Biostatistics, Washington University School of Medicine, St. Louis

1995-1998 Associate to Acting Director, Center for Special Populations and Health, The Pennsylvania State University, University Park

1995-2001 Associate Professor of Biobehavioral Health and Associate Director, Center for Special Populations and Health, The Pennsylvania State University, University Park

1998-2001 Associate Director, Center for Developmental and Health Genetics, The Pennsylvania State University, University Park

2001-Present Professor of Biobehavioral Health, The Pennsylvania State University

2002-Present Director, Center for Developmental and Health Genetics, The Pennsylvania State University


SELECTED PUBLICATIONS: 

Perusse, L. , T. Rice , C. Bouchard , G.P. Vogler and D.C. Rao (1989). "Cardiovascular Risk Factors in a French Canadian Population: Resolution of Genetic and Familial Environmental Effects on Blood Pressure Using Extensive Information on Environmental Correlates." American Journal of Human Genetics 45(2):240-251. PMCID: PMC1683357?? |Full Text| |Abstract| |Journal Home Page|

Rice, T. , G.P. Vogler , L. Perusse , C. Bouchard and D.C. Rao (1989). "Cardiovascular Risk Factors in a French Canadian Population: Resolution of Genetic and Familial Environmental Effects on Blood Pressure Using Twins, Adoptees and Extensive Information on Environmental Correlates." Genetic Epidemiology 6(5):571-588. |Abstract| |Journal Home Page|

Vogler, G.P. , L.A. Baker , S.N. Decker , J.C. DeFries and D.H. Huizinga (1989). "Cluster Analytic Classification of Reading Disability Subtypes." Reading and Writing 1:163-177. |Journal Home Page|

Vogler, G.P. , R. Wette , P.M. Laskarzewski , T.S. Perry , T. Rice , M.A. Province and D.C. Rao (1989). "Heterogeneity in the Biological and Cultural Determinants of High Density Lipoprotein Cholesterol in Five North American Populations: The Lipid Research Clinics Family Study." Human Heredity 39(5):249-257. |Abstract| |Journal Home Page|

Rice, T. , G.P. Vogler , T.S. Perry , P.M. Laskarzewski , M.A. Province and D.C. Rao (1990). "Heterogeneity in the Familial Aggregation of Fasting Plasma Glucose in Five North American Populations: The Lipid Research Clinics Family Study." International Journal of Epidemiology 19(2):290-296. |Abstract| |Journal Home Page|

Vogler, G.P. , I.I. Gottesman , M. McGue and D.C. Rao (1990). "Mixed Model Segregation Analysis of Schizophrenia in the Lindelius Swedish Pedigrees." Behavior Genetics 20(4):461-472. |Abstract| |Journal Home Page|

Rice, T. , G.P. Vogler , P.M. Laskarzewski , T.S. Perry and D.C. Rao (1991). "Familial Aggregation of Lipids and Lipoproteins in Families Ascertained through Random and Nonrandom Probands in the Stanford Lipid Research Clinics Family Study." American Journal of Medical Genetics 39(3):270-277. |Abstract| |Journal Home Page|

Province, M.A. , I.B. Borecki , T. Rice and G.P. Vogler (1992). "Investigation of Major Gene and Covariate Effects Using a New Poisson Process Model." Cytogenetics and Cell Genetics 59(2-3):223-224. |Journal Home Page|

Vogler, G.P. and D.C. Rao (1993). "Path Analysis in Genetic Epidemiology: Theory and Applications." In Majumder, P.P. (Ed.) , Modern human genetics: A centennial tribute to J.B.S. Haldane. New York, NY: Plenum. (pp. 291-304)

Newcomer, J.W. , L.S. Miller , W.O. Faustman , M.W. Wetzel , G.P. Vogler and J.G. Csernansky (1994). "Correlations between Akathisia and Residual Psychopathology: A By-Product of Neuroleptic-Induced Dysphoria." British Journal of Psychiatry 164(6):834-838. |Abstract| |Journal Home Page|

Borecki, I.B. and G.P. Vogler (1995). "Interval Mapping of Quantitative Trait Loci Using a Sib-Pair Linkage Method." Genetic Epidemiology 12(6):723-728. |Abstract| |Journal Home Page|

Durham, R. , K. Neunaber , G.P. Vogler , M. Shapiro and J. Mazuski (1995). "Right Ventricular End Diastolic Volume as a Measure of Preload." Journal of Trauma 39(2):218-223. |Abstract| |Journal Home Page|

Gynther, L.M. , G. Carey , I.I. Gottesman and G.P. Vogler (1995). "A Twin Study of Non-Alcohol Substance Abuse." Psychiatry Research 56(3):213-220. |Abstract| |Journal Home Page|

Haller, B.L. , M.L. Barkon , G.P. Vogler and H.W. Virgin (1995). "Genetic Mapping of Reovirus Virulence and Organ Tropism in Severe Combined Immunodeficient Mice: Organ Specific Virulence Genes." Journal of Virology 69(1):357-364. PMCID: PMC188583?? |Full Text| |Abstract| |Journal Home Page|

Vogler, G.P. , T.I. Sorensen , A.J. Stunkard , M.R. Srinivasan and D.C. Rao (1995). "Influences of Genes and Shared Family Environment on Adult Body Mass Index Assessed in an Adoption Study by a Comprehensive Path Model." International Journal of Obesity 19(1):40-45. |Abstract| |Journal Home Page|

Chicoine, M.R. , T.S. Park , G.P. Vogler and B.A. Kaufman (1996). "Predictors of Ability to Walk After Selective Dorsal Rhizotomy in Children With Cerebral Palsy." Neurosurgery 38(4):711-714. |Abstract| |Journal Home Page|

McClearn, G.E. , G.P. Vogler and R. Plomin (1996). "Genetics and Behavioral Medicine." Behavioral Medicine 22(3):93-102. |Abstract| |Journal Home Page|

McClearn, G.E. and G.P. Vogler (1997). "Genetics and Behavioral Medicine: Error of the Error Term." Behavioral Medicine 22(4):150-151. |Journal Home Page|

Vogler, G.P. , G.E. McClearn , H. Snieder , D.I. Boomsma , R. Palmer , P. de Knijff and P.E. Slagboom (1997). "Genetics and Behavioral Medicine: Risk Factors for Cardiovascular Disease." Behavioral Medicine 22(4):141-149. |Abstract| |Journal Home Page|

Vogler, G.P. , W. Tang , T.L. Nelson , S.M. Hofer , J.D. Grant , L.M. Tarantino and J.R. Fernandez (1997). "A Multivariate Model for the Analysis of Sibship Covariance Structure Using Marker Information and Multiple Quantitative Traits." Genetic Epidemiology 14(6):921-926. |Abstract| |Journal Home Page|

Bonneau, R.H. , P. Mormede , G.P. Vogler , G.E. McClearn and B.C. Jones (1998). "A Genetic Basis for Neuroendocrine-Immune Interactions." Brain, Behavior, & Immunity 12(2):83-89. |Abstract| |Journal Home Page|

Kozlowski, L.T. , N.Y. Mehta , C.T. Sweeney , S.S. Schwartz , G.P. Vogler , M.J. Jarvis and R.J. West (1998). "Filter Ventilation and Nicotine Content of Tobacco in Cigarettes from Canada, the United Kingdom, and the United States." Tobacco Control 7(4):369-375. PMCID: PMC1751464?? |Abstract| |Journal Home Page|

Newcomer, J.W. , G. Selke , A.K. Melson , J. Gross , G.P. Vogler and S. Dagogo-Jack (1998). "Dose-Dependent Cortisol-Induced Increases in Plasma Leptin Concentration in Healthy Humans." Archives of General Psychiatry 55(11):995-1000. |Abstract| |Journal Home Page|

Newcomer, J.W. , S. Craft , K. Askins , T. Hershey , M.E. Bardgett , J.G. Csernansky , A.E. Gagliardi and G.P. Vogler (1998). "Glucocorticoid Interactions with Memory Function in Schizophrenia." Psychoneuroendocrinology 23(1):65-72. |Abstract| |Journal Home Page|

Todorov, A.A. , G.P. Vogler , C. Gu , M.A. Province , Z. Li , A.C. Heath and D.C. Rao (1998). "Testing Causal Hypotheses in Multivariate Linkage Analysis of Quantitative Traits: General Formulation and Application to Sibpair Data." Genetic Epidemiology 15(3):263-278. |Abstract| |Journal Home Page|

Vogler, G.P. and J.T. Quirk (1998). "Genetics of Blood Pressure Variations in Humans." In McCarty, R. , D.A. Blizard and R.L. Chevalier (Eds.) , Development of the hypertensive phenotype: Basic and clinical studies. Amsterdam: Elsevier. (pp. 575-586)

Fernandez, J.R. , G.P. Vogler , L.M. Tarantino , S. Vignetti , R. Plomin and G.E. McClearn (1999). "Sex-Exclusive Quantitative Trait Loci Influences in Alcohol-Related Phenotypes." American Journal of Medical Genetics 88(6):647-652. |Abstract| |Journal Home Page|

Nelson, T.L. , G.P. Vogler , N.L. Pedersen and T.P. Miles (1999). "Genetic and Environmental Influences on Waist-To-Hip Ratio and Waist Circumference in an Older Swedish Twin Population." International Journal of Obesity and Related Metabolic Disorders 23(5):449-455. |Abstract| |Journal Home Page|

Nelson, T.L. , G.P. Vogler , N.L. Pedersen and Y. Hong (1999). "Implications of Body Fat Distribution in an Older Twin Population." Journals of Gerontology 54A(9):M446-M450. |Abstract| |Journal Home Page|

Vogler, G.P. (1999). "Partitioning the Genetic Variation of Quantitative Traits Using Marker Loci." In LaBuda, M.C. and E.L. Grigorenko (Eds.) , On the Way to Individuality. Nova Publishers. (pp. 235-247)

Fernandez, J.R. , L.M. Tarantino , S.M. Hofer , G.P. Vogler and G.E. McClearn (2000). "Epistatic Quantitative Trait Loci for Alcohol Preference in Mice." Behavioral Genetics 30(6):431-437. |Abstract| |Journal Home Page|

Nelson, T.L. , G.P. Vogler , N.L. Pedersen , Y. Hong and T.P. Miles (2000). "Genetic and Environmental Influences on Body Fat Distribution, Fasting Insulin Levels and CVD: Are the Influences Shared?." Twin Research 3(1):43-50. |Abstract| |Journal Home Page|

Pardo, P.J. , M.A. Knesevich , G.P. Vogler , J.V. Pardo , B. Towne , C.R. Cloninger and M.I. Posner (2000). "Genetic and State Variables of Neurocognitive Dysfunction in Schizophrenia: A Twin Study." Schizophrenia Bulletin 26(2):459-477. |Abstract| |Journal Home Page|

Beekman, M. , N. Lakenberg , S.S. Cherny , P. de Knijff , C.C. Kluft , G.B. van Ommen , G.P. Vogler , R.R. Frants , D.I. Boomsma and P.E. Slagboom (2001). "A Powerful and Rapid Approach to Genome Scanning Using Small Quantities of Genomic DNA." Genetical Research 77(2):129-134. |Abstract| |Journal Home Page|

McClearn, G.E. and G.P. Vogler (2001). "The Genetics of Behavioral Aging." In Birren, J.E. and K.W. Schaie (Eds.) , Handbook of the Psychology of Aging, Fifth Edition. San Diego: Academic Press.

McClearn, G.E. , G.P. Vogler and S.M. Hofer (2001). "Environment-Gene and Gene-Gene Interactions." In Masoro, E.J. and S.N. Austad (Eds.) , Handbook of the Biology of Aging, 5th ed.. Von Nostrand Reinhold. (pp. 423-444)

Quirk, J.T. , S. Berg , V.M. Chinchilli , B. Johansson , G.E. McClearn and G.P. Vogler (2001). "Modelling Blood Pressure as a Continuous Outcome Variable in a Co-Twin Control Study." Journal of Epidemiology and Community Health 55(10):746-747. PMCID: PMC1731777?? |Full Text| |Journal Home Page|

Vogler, G.P. (2001). "The Value of Sibling and Other 'Relational' Data for Biodemography and Genetic Epidemiology." In Finch, C.E. and J.W. Vaupel (Eds.) , Cells and Surveys: Should Biological Measures Be Included in Social Science Research?. Washington, D.C.: National Academy Press.

Beekman, M. , B.T. Heijmans , N.G. Martin , N.L. Pedersen , J.B. Whitfield , U. DeFaire , G.C. van Baal , H. Snieder , G.P. Vogler , P.E. Slagboom and D.I. Boomsma (2002). "Heritabilities of Apolipoprotein and Lipid Levels in Three Countries." Twin Research 5(2):87-97. |Abstract| |Journal Home Page|

Kozlowski, L.T. , G.P. Vogler , D.J. Vandenbergh , A.A. Strasser , R.J. O'Connor and B.A. Yost (2002). "Using a Telephone Survey to Acquire Genetic and Behavioral Data Related to Cigarette Smoking in "Made-Anonymous" and "Registry" Samples." American Journal of Epidemiology 156(1):68-77. |Abstract| |Journal Home Page|

Vandenbergh, D.J. , C.J. Bennett , M.D. Grant , A.A. Strasser , R.J. O'Connor , R.L. Stauffer , G.P. Vogler and L.T. Kozlowski (2002). "Smoking Status and the Human Dopamine Transporter Variable Number of Tandem Repeats (VNTR) Polymorphism: Failure to Replicate and Finding That Never-Smokers May Be Different." Nicotine and Tobacco Research 4(3):333-340. |Abstract| |Journal Home Page|

Vandenbergh, D.J. , L.T. Kozlowski , C.J. Bennett , M.D. Grant , A.A. Strasser , R.J. O'Connor , R.L. Stauffer and G.P. Vogler (2002). "DAT's Not All, But It May Be More Than We Realize." Nicotine and Tobacco Research 4(3):251-252. |Journal Home Page|

Vogler, G.P. and L.T. Kozlowski (2002). "Differential Influence of Maternal Smoking on Infant Birth Weight: Gene-Environment Interaction and Targeted Intervention." JAMA: The Journal of the American Medical Association 287(2):241-242. |Journal Home Page|

Beekman, M. , B.T. Heijmans , N.G. Martin , J.B. Whitfield , N.L. Pedersen , U. DeFaire , H. Snieder , N. Lakenberg , H.D. Suchiman , P. de Knijff , R.R. Frants , G.B. van Ommen , C.C. Kluft , G.P. Vogler , D.I. Boomsma and P.E. Slagboom (2003). "Evidence for a Qtl on Chromosome 19 Influencing Ldl Cholesterol Levels in the General Population." European Journal of Human Genetics 11(11):845-850. |Abstract| |Journal Home Page|

Brandon, D.T. , K.E. Whitfield , J.J. Sollers , S.A. Wiggins , S.G. West , G.P. Vogler , G.E. McClearn and J.F. Thayer (2003). "Genetic and Environmental Influences on Blood Pressure and Pulse Pressure among Adult African Americans." Ethnicity and Disease 13(2):193-199. |Abstract| |Journal Home Page|

Brandon, D.T. , K.E. Whitfield , J.J. Sollers , S.A. Wiggins , S.G. West , G.P. Vogler , G.E. McClearn and J.F. Thayer (2003). "The Nature and Nurture of Blood Pressure in African Americans." Ethnicity and Disease 13(2):297-298. |Journal Home Page|

Kerin, T.K. , G.P. Vogler , D.A. Blizard , J.T. Stout , G.E. McClearn and D.J. Vandenbergh (2003). "Anogenital Distance Measures at Weaning is Correlated with Measures of Blood Chemistry and Behaviors in 450-Day-Old Female Mice." Physiology and Behavior 78(4-5):697-702. |Abstract| |Journal Home Page|

Lionikas, A. , D.A. Blizard , D.J. Vandenbergh , M.G. Glover , J.T. Stout , G.P. Vogler , G.E. McClearn and L. Larsson (2003). "Genetic Architecture of Fast- and Slow-Twitch Skeletal Muscle Weight in 200-Day-Old Mice of the C57BL/6J and DBA/2J Lineage." Physiological Genomics 16(1):141-152. |Full Text| |Abstract| |Journal Home Page|

Vandenbergh, D.J. , K. Heron , R. Peterson , K.B. Shpargel , A. Woodroffe , D.A. Blizard , G.E. McClearn and G.P. Vogler (2003). "Simple Tests to Detect Errors in High-Throughput Genotype Data in the Molecular Laboratory." Journal of Biomolecular Techniques 14(1):9-16. PMCID: PMC2279894?? |Abstract| |Journal Home Page|

Whitfield, K.E. , D.T. Brandon , S.A. Wiggins , G.P. Vogler and G.E. McClearn (2003). "Does Intact Pair Status Matter in the Study of African American Twins?: The Carolina African American Twin Study of Aging." Experimental Aging Research 29(4):407-423. |Abstract| |Journal Home Page|

Beekman, M. , D. Posthuma , B.T. Heijmans , N. Lakenberg , H.D. Suchiman , H. Snieder , P. de Knijff , R.R. Frants , G.B. van Ommen , C.C. Kluft , G.P. Vogler , P.E. Slagboom and D.I. Boomsma (2004). "Combined Association and Linkage Analysis Applied to the APOE Locus." Genetic Epidemiology 26(4):328-337. |Abstract| |Journal Home Page|

Blizard, D.A. , D.J. Vandenbergh , A.L. Jefferson , C.D. Chatlos , G.P. Vogler and G.E. McClearn (2004). "Effects of Periadolescent Ethanol Exposure on Alcohol Preference in Two BALB Substrains." Alcohol 34(2-3):177-185. |Abstract| |Journal Home Page|

Foreman, J.E. , D.A. Blizard , G.S. Gerhard , H.A. Mack , D.H. Lang , K.L. Van Nimwegen , G.P. Vogler , J.T. Stout , Z.K. Shihabi , J.W. Griffith , J.M. Lakoski , G.E. McClearn and D.J. Vandenbergh (2005). "Serum Alkaline Phosphatase Activity is Regulated by a Chromosomal Region Containing the Alkaline Phosphatase 2 Gene (Akp2) in C57BL/6J and DBA/2J Mice." Physiological Genomics 23(3):295-303. |Abstract| |Journal Home Page|

Lang, D.H. , N.A. Sharkey , A. Lionikas , H.A. Mack , L. Larsson , G.P. Vogler , D.J. Vandenbergh , D.A. Blizard , J.T. Stout , J.P. Stitt and G.E. McClearn (2005). "Adjusting Data to Body Size: A Comparison of Methods as Applied to Quantitative Trait Loci Analysis of Musculoskeletal Phenotypes." Journal of Bone and Mineral Research 20(5):748-757. PMCID: PMC1201530?? |Abstract| |Journal Home Page|

Lang, D.H. , N.A. Sharkey , H.A. Mack , G.P. Vogler , D.J. Vandenbergh , D.A. Blizard , J.T. Stout and G.E. McClearn (2005). "Quantitative Trait Loci Analysis of Structural and Material Skeletal Phenotypes in C57BL/6J and DBA/2 Second-Generation and Recombinant Inbred Mice." Journal of Bone and Mineral Research 20(1):88-99. PMCID: PMC1201529?? |Abstract| |Journal Home Page|

Lionikas, A. , D.A. Blizard , G.S. Gerhard , D.J. Vandenbergh , J.T. Stout , G.P. Vogler , G.E. McClearn and L. Larsson (2005). "Genetic Determinants of Weight of Fast- and Slow-Twitch Skeletal Muscle in 500-day Old Mice of the C57BL/6J and DBA/2J Lineage." Physiological Genomics 21(2):184-192. |Abstract| |Journal Home Page|

O'Connor, R.J. , L.T. Kozlowski , D.J. Vandenbergh , A.A. Strasser , M.D. Grant and G.P. Vogler (2005). "An Examination of Early Smoking Experiences and Smoking Status in a National Cross-Sectional Sample." Addiction 100(9):1352-1357. |Abstract| |Journal Home Page|

Prescott, C.A. , C.B. Caldwell , G. Carey , G.P. Vogler , S.L. Trumbetta and I.I. Gottesman (2005). "The Washington University Twin Study of Alcoholism." American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 134B(1):48-55. |Abstract| |Journal Home Page|

Bower, A.L. , D.H. Lang , G.P. Vogler , D.J. Vandenbergh , D.A. Blizard , J.T. Stout , G.E. McClearn and N.A. Sharkey (2006). "QTL Analysis of Trabecular Bone in BXD F-2 and RI Mice." Journal of Bone and Mineral Research 21(8):1267-1275. |Abstract| |Journal Home Page|

Lionikas, A. , M.G. Glover , F. Yu , L. Larsson , G.P. Vogler , G.E. McClearn and D.A. Blizard (2006). "Anomaly of Anatomical Origin of Soleus Muscle: A Mouse Model." Anatomical Science International 81(1):47-49. |Abstract| |Journal Home Page|

Read, S. , G.P. Vogler , N.L. Pedersen and B. Johansson (2006). "Stability and Change in Genetic and Environmental Components of Personality in Old Age." Personality and Individual Differences 40(8):1637-1647. |Abstract| |Journal Home Page|

Vogler, G.P. (2006). "Behavior Genetics and Aging." In Birren, J.E. (Ed.) , Handbook of the Psychology of Aging (6th ed.). Amsterdam: Elsevier. (pp. 41-55)

Vandenbergh, D.J. , R.J. O'Connor , M.D. Grant , A.L. Jefferson , G.P. Vogler , A.A. Strasser and L.T. Kozlowski (2007). "Dopamine Receptor Genes (DRD2, DRD3 and DRD4) and Gene-Gene Interactions Associated with Smoking-Related Behaviors." Addiction Biology 12(1):106-116. |Abstract| |Journal Home Page|

Vogler, G.P. and G.E. McClearn (2008). "Genetic Markers in Social Science Research: Opportunities and Pitfalls." In Weinstein, M. , J.W. Vaupel and K.W. Wachter (Eds.) , Biosocial Surveys. Washington, DC: National Academies Press. (pp. 194-207) |Full Text|

Blizard, D.A. , A. Lionikas , D.J. Vandenbergh , T. Vasilopoulos , G.S. Gerhard , J.W. Griffith , L.C. Klein , J.T. Stout , H.A. Mack , J.M. Lakoski , L. Larsson , J.M. Spicer , G.P. Vogler and G.E. McClearn (2009). "Blood Pressure and Heart Rate QTL in Mice of the B6/D2 Lineage: Sex Differences and Environmental Influences." Physiological Genomics 36(3):158-166. PMCID: PMC2646459?? |Abstract| |Journal Home Page|

Whitfield, K.E. , X. Yao , K.B. Boomer , G.P. Vogler , M.D. Hayward and D.J. Vandenbergh (2009). "Analysis of Candidate Genes and Hypertension in African American Adults." Ethnicity & Disease 19(1):18-22. |Abstract| |Journal Home Page|

Foreman, J.E. , A. Lionikas , D.H. Lang , J.P. Gyekis , M. Krishnan , N.A. Sharkey , G.S. Gerhard , M.D. Grant , G.P. Vogler , H.A. Mack , J.T. Stout , J.W. Griffith , J.M. Lakoski , S.M. Hofer , G.E. McClearn , D.J. Vandenbergh and D.A. Blizard (Forthcoming). "Genetic Architecture for Hole-Board Behaviors across Substantial Time Intervals in Young, Middle-Aged and Old Mice." Genes, Brain and Behavior. |Abstract| |Journal Home Page|

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