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Grant and Funding Opportunity Announcements

Novel Approaches for Assessing Exposure for School-Aged Children in Longitudinal Studies Open to non-US citizens

Application Deadline: 11/18/2008
A key issue faced by researchers conducting large population studies of children's environmental health is the challenge of assessing exposure. Traditional exposure assessment methods depend on questionnaires and multiple environmental samples, but these tend to be costly and create a burden of time and effort for both study participants and researchers. There is also little information about how exposures change over time as children age and begin to spend more time outside the home in places such as child care locations, schools and playgrounds. Research is needed to assess whether there are differences in nonresidential environments that may lead to changes in exposure estimates and/or classifications for children. The U.S. Environmental Protection Agency (EPA), as part of its Science to Achieve Results (STAR) program, is soliciting applications proposing research to develop and evaluate novel, innovative approaches for classifying exposure for children 2 to <11 years of age to toxic chemicals in their environment for use in large-scale longitudinal exposure assessment and epidemiological studies.

These approaches could include the use of targeted direct and indirect exposure related measurements, biological markers (biomarkers), questionnaires and surveys, community and regional-level measurements, mathematical models and classification schemes and informatic approaches such as principal component analysis. The methods and/or tools developed and evaluated could include an exposure index that could be used to characterize and classify individual exposure status (for example, high, medium, or low) of children for exposure to chemical agents and other environmental factors across life stages.

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Funding Agencies:
- National Center for Environmental Research (NCER)

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